WebHTB-161 ™. NIH:OVCAR-3 [OVCAR3] are epithelial cells that were isolated in 1982 from the malignant ascites of a patient with progressive adenocarcinoma of the ovary. Use these cells to study drug resistance in ovarian cancer. Product category. WebTo cite this cell line use: OVCAR-3 (RRID:CVCL_0465) Comments Part of: AKT genetic alteration cell panel (ATCC TCP-1029). Part of: Cancer Dependency Map project …
BRCA1/2 mutation analysis in 41 ovarian cell lines reveals
WebIt describes the source of the mutation i.e gene name/sample name/tissue name with unique ID, and also shows the mutation syntax at the amino acid and nucleotide sequence level. You can see more information on our help pages . Genomic Mutation ID COSV52661282 Legacy Identifier COSM10758 Gene name TP53 AA mutation WebJul 24, 2024 · Basal phosphorylated (pCHK1) and total CHK1 levels were also especially increased in CCNE1AMP lines (OVCAR3, FUOV1, and COV318), consistent with high levels of replication stress 49, 50 in these... lehigh university phd english
High-grade serous ovarian cancer cell lines exhibit …
WebThe Caov-3 cells harbor a nonsense mutation in the p53 gene, and have multiple copies of the ovarian cancer oncogene PIK3CA. They are sensitive to vinblastine, cisplatin, and … WebJul 1, 2024 · We found that, with the exception of OVCAR3, HGSC cell lines COV318, COV362, KURAMOCHI, OVCAR4, and OVSAHO, generally demonstrate poor growth as either subcutaneous or intraperitoneal xenografts.... WebJun 30, 2011 · Molecular analysis of the WNT4 gene permitted us to identify a new mutation (p.A233T). Functional studies revealed partial repression of steroidogenic enzymes (normal repression of HSD3B2) contrasting with the abnormal reexpression of CYP17A1 enzyme in the OVCAR3 cell line. lehigh university parents weekend 2022